The SharePoint Foundation 2010 object model is not accessible using the .NET Framework 4 (or later). Calling any object or method in the object model using any framework version other than .NET 3.5 will throw the following exception:
Microsoft SharePoint is not supported with version 4.0.30319.1 of the Microsoft .Net Runtime.
Of course, you can always access the SharePoint objects using the web services interface from your .NET 4 application, but this will only allow limited functionality of the complete object model.
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Aug 19 2010, 08:00 AM